Clinical Immunology

Overview

This one-day intensive course aims to provide an integrated overview of central concepts in clinical immunology, with a focus on the relationship between fundamental immune mechanisms and their relevance to human health and disease.

The program is designed to guide participants from the core principles of immune function to their clinical and translational applications. Topics include T cell biology and immune regulation, primary and secondary immunodeficiencies, immune modulation in organ transplantation, tumor immunology, controlled human infection models, autoimmune and allergic diseases, vaccination, and clinical trial design. Together, these sessions emphasize immune regulation as a common thread across diverse immunological conditions and therapeutic approaches.

Directed by Dr. Alexis Kalergis, the course brings together internationally recognized experts who integrate basic, translational, and clinical perspectives. Through this approach, the course aims to enhance participants’ understanding of how advances in immunology inform clinical decision-making and the development of new therapeutic strategies.

Target Audience

This course is intended for translational researchers and scientists, practicing clinicians with an interest in clinical immunology, and clinical and research trainees seeking to deepen their understanding of immune mechanisms in human health and disease. It is also relevant for professionals in the biotechnology and pharmaceutical sectors who develop immune-based diagnostics, vaccines, and therapies.

The course is particularly suitable for participants with prior training in immunology, the biomedical sciences, or related disciplines who seek an integrated perspective on immune regulation across a range of clinical contexts, including infection, immunodeficiency, autoimmunity, allergy, transplantation, vaccination, and cancer.

Learning Objectives

After the course, attendees will be able to:

• Describe the fundamental mechanisms of immune function and regulation and explain how their dysregulation contributes to human disease.
• Explain the role of T cells and other immune components in maintaining immune homeostasis and in the development of pathological immune responses.
• Discuss the clinical immunology of primary and secondary immunodeficiencies, autoimmunity, allergy, transplantation, infection, and cancer, emphasizing shared mechanisms of immune regulation.
• Analyze immune responses in different clinical contexts, including infection, autoimmunity, transplantation, vaccination, and tumor immunity.
• Describe the mechanisms underlying immune modulation in cancer, including immune checkpoint pathways and selected immunotherapeutic strategies.
• Identify immune-related adverse events associated with immunomodulatory therapies and discuss their clinical implications and management challenges.
• Discuss the immunological principles underlying vaccination, including mechanisms of efficacy and emerging challenges.
• Evaluate emerging translational approaches in clinical immunology, including controlled human infection models and principles of clinical trial design.

Alexis Kalergis, PhD

Pontificia Universidad Católica de Chile

2026 Agenda 

(PST) Time Zone

Registration Rates